2017 Call for Abstracts
The SVS is accepting abstract
and video submissions for the
2017 Vascular Annual Meeting from
November 14, 2016 — January 25, 2017
To review abstract guidelines and for
more information, visit
fat diet demonstrated significantly delayed wound
healing compared to the mice fed a normal diet. As
researchers had hypothesized, there were increased
levels of detectable TLR4 RNA and protein in the
bone marrow, blood and wounds of the high-fat diet
mice. Given these findings of increased systemic expression of TLR4, the researchers deduced that there
may be an epigenetic component to the increased
expression patterns. Using chromatin immunoprecip-itation analysis (ChIP) they found increased levels of
histone methylation marks at the TLR4 gene locus
that would allow and promote gene transcription.
“This is an interesting finding for two reasons,” said
Dr. Kimball. “First, it demonstrates how diabetes is
a true systemic illness as it affects cells all over the
body. Second, diabetes goes as far as altering the DNA
software which can irreversibly affect cell function
for life.” The team concluded that diabetes results in
wound monocyte/macrophages that have an inflam-
matory predisposition and this may represent a target
Overall goals for the project were to inform researchers of novel targets for the treatment of chronic
non-healing diabetic wounds. A secondary potential
goal was to develop parameters and immunological
tests that may help inform physicians of prognosis
and to determine feasibility of limb salvage procedures.
“A logical follow-up study to the VRIC work
would be to examine the expression patterns of his-tone-modifying enzymes in diabetic macrophages and
to try to find the enzyme that is resulting in these
epigenetic changes and, in turn, how that enzyme is
affected by the diabetic milieu,” said Dr. Kimball.
Dr. Gallagher’s team is now working on a separate
project, also in diabetes, that members hope to present at VRIC 2017. The study abstract is available at
NEWS FROM SVS
Focus continued from page 10
Take a Peak at
Among the articles of interest to SVS members in the November
issue of the Journal of Vascular Surgery
are those on treatment of the femoro-popliteal artery with the bioresorbable
REMEDY stent, AAA surgery for
infants and young children, a VQI
Cardiac Risk Index and much more.
these and all the other content in the
November JVS as well as video introductions to articles presented by SVS
Co-Editor Dr. Peter Gloviczki. ■
Veterans Day: An SVS Member Remembers MASH
Experience During the Korean War
This is November, the month of Veterans Day. And the experi- ence of being a surgeon during
war is one of the highlights of the
SVS History Project Work Group’s
new video, an interview with Dr.
Milton Weinberg, a member since
Most of the previous interviews for
the work group’s project have been
with SVS past presidents. However,
said Dr. James Yao, former chair of
the history team, group members
thought SVS members would find Dr.
Weinberg’s recollections interesting.
“He’s been a member for so long and
has experienced a great many chang-
es,” said Dr. Yao. “We wanted to see
what he had to say about the SVS.”
In addition to Dr. Weinberg’s work
as a doctor and mentor, “respected
by everybody,” said Dr. Yao, Dr.
Weinberg also was an Army surgeon
who served in Korea.
Because he had three years of
surgical experience, Dr. Weinberg
served for approximately six months
of his time in Korea in a Mobile
Army Surgical Hospital – or MASH –
unit, made famous in the 1970 black
comedy movie, “MASH,” and the
long-running television series of the
In his interview, Dr. Weinberg
noted that during World War II, Dr.
had been a driving
force for the concept
of a unit that moved
as the troops did
and took care of the
close to the action.
MASH unit loca-
tions varied from
seven or so miles to
miles from the fight-
ing. “It was a dis-
tance an ambulance
could get to in a
reasonable amount of time,” said Dr.
Weinberg, with helicopters used to
bring in the most seriously injured.
He noted that 97 percent of all
wounded soldiers brought to a
MASH unit survived. Never before
had survival rates been so high.
As someone who served in Korea,
what does Dr. Weinberg think of the
“I liked the movie, because it was
funny,” he said. “I didn’t like the TV
series (known as “M*A*S*H”), because
they belittled the Regular Army.” And
it is the so-called Regular Army, he said,
“that takes the brunt of the real fight-
ing when a war first starts.”
It is thought that the character
Hawkeye Pierce was modeled at least
partially after the late Dr. Keith Re-
emtsma, of Columbia Presbyterian
Medical Center, and an SVS member,
Dr. Yao added in the interview.
Dr. Weinberg said he – and prob-
ably all soldiers – left Korea, “A little
bit older than when we came in, a
little more serious.”
To watch the interview, visit
Doctors operate in Korean War MASH unit.